Research | The NIMHANS Brain Bank

Non Funded Projects

S. No	Project Name and Details
1	Molecular Profiling of Temporal Lobe epilepsy PI: Dr.Akhilesh Pandey, Institute of Bioinformatics, Bangalore Co-PI: Dr.SK Shankar, Dept of Neuropathology and Prof P Satishchandra, Dept of Neurology, NIMHANS
2	Towards new diagnostics of tuberculosis: detection of antibody to mycobacterium tuberculosis in CSF of Tuberculous meningitis patients. PI: Dr. A Chandramuki, Prof & Head, Department of Neuromicrobiology, NIMHANS, Bangalore.
3	Changes in Brain Gene Expression following infections by neurotropic viruses. PI: Prof.P.N.Rangarajan, Dept of biochemistry, Indian Institute of Science, Bangalore / HBTR, NIMHANS
4	Trace metal estimation in CSF. PI: Dr.V. Krishnamurthy, Assistant Director, Regional Occupational Health Centre, (Southern), Bangalore, ICMR / HBTR, NIMHANS.
5	Genetics of progressive Myoclonic Epilepsy in the Indian population. PI: Dr.S.Ganesh, Asst Prof. Dept of Biological Sciences & Bio-Engineering, IIT, Kanpur / Prof.P.Satishchandra, Dept of Neurology & HBTR, NIMHANS.
6	Molecular correlation of pathological features in CNS infections in HIV – Cerebral toxoplasmosis and CMV encephalitis Pl: Jayashree RS, Prof, Dept of Microbiology, Kidwai Memorial Institute of Oncology, Bangalore/ HBTR, NIMHANS Co-PI: Dr.SK Shankar, Dr.Anita Mahadevan, Department of Neuropathology, NIMHANS, Bangalore
7	Seroprevalence of Toxoplasmosis, CMV and VZV in adult, health, voluntary blood donors in Karnataka. PI: Dr. Sundar Periyavan, Transfusion Medicine Centre, Dept of Neuropathology, NIMHANS, Bangalore. Co-PI: Dr.SK Shankar, Dr.Anita Mahadevan, Department of Neuropathology, NIMHANS, Bangalore
8	Biochemical and histological analysis of human brain in ageing and neurodegeneration PI: Dr.Srinivas Bharath, Asst Professor, Dept of Neurochemistry, NIMHANS, Bangalore Co-PI: Dr.SK Shankar, Professor, Department of Neuropathology, NIMHANS, Bangalore
9	ApoE genetic polymorphism and its association with outcome in cases of traumatic head injury Collaboration with Prof.B.K.Thelma Kutappa, Dept of Human Genetics, Delhi University and Prof. B A Chandramouli and Dr. Nupur Pruthi, Dept of neurosurgery, NIMHANS, HBTR, Department of Neuropathology, NIMHANS).
10	Ageing changes in microglia in Hippocampus- Frontal Cortex PI: Dr.Nisha Patro and Ishan Patro, School of Studies in Neurosciences, Jiwaji University, Gwalior, MP, and HBTR, Department of Neuropathology NIMHANS, Bangalore).
11	Molecular Studies on Lead (Pb) levels, DNA topology and cellular damage in ageing human brain. PI: Dr.K.S.Jagannatha Rao, CFTRI Mysore, Dr .M.M.Shama Sundar, Department Anatomy, J.S.S.Medical College, Mysore, HBTR, Department of Neuropathology, NIMHANS, Bangalore.
12	Role of Cerebral cysticercosis in the evolution of epileptic focus in the Brain. PI: Dr.Ishan Patro, School of Studies in Neuroscience, Jiwaji University, Gwalior HBTR, Dept. of Neuropathology, NIMHANS
13	Expanded conceptor use of Human Immunodeficiency Virus Type-1, subtype C molecular clones isolated from an Indian demented subject – implications for HIV-1 associated dementia. PI: Dr.Ranga Uday Kumar, JNCASR Co-PI: Dr.P.Satishchandra, Dept. of Neurology, NIMHANS, Dr.Anita Mahadevan and Dr.S.K.Shankar, HBTR, Dept. of Neuropathology, NIMHANS, Bangalore.
14	Developmental and pathological expression of BCAS3, a conserved WD40 protein. PI: Dr. Maneesha S.Inamdar, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore Co-PI: HBTR, Dept of neuropathology, Bangalore
15	Phylogenetic study of measles virus and molecular genetic identification of genotype D7 in a ultra short case of SSPE from South India. PI: Dr.Niteen S.Wairagnar, National Institute of Virology (NIV), Pune Co-PI: HBTR, Dept of neuropathology, Bangalore
16	Mutations at the extracellular calcium sensing Receptor gene, CSAR in the idiopathic generalized epilepsy. PI: Dr.Anuranjan Anand, Dr.Ashish Kapoor, Molecular Biology and Genetics Unit, JNCASR; Co-PI: Prof.P.Satishchandra, Dept. of Neurology, NIMHANS, Dr.J.Kadandale Centre for Human Genetics, ITPB
17	Tuberculous Meningitis: Immunodiagnosis and Cytokine studies PI: Collaboration with Dr. Sripad Patil, Additional Professor, Neuromicrobiology Co-PI: Dr.Anita Mahadevan, Dr. S.K.Shankar, HBTR, Department of Neuropathology, NIMHANS, Bangalore
18	Cytokine response in tropical infections of relevance to India including Rabies, cerebral malaria and Cryptococcal Meningitis. PI: Dr. Sripad Patil, Additional Professor, Neuromicrobiology Co-PI: Dr.Anita Mahadevan, Dr. Suja M and Dr. S.K.Shankar, Department of Neuropathology, NIMHANS, Bangalore
19	Lafora body disease – role of Malin and ubiquitin-proteosome pathway in pathogenesis PI: Dr.Nihar Rejan Jena, Dr,Sudheendra Rao National Brain Research Centre, Gurgaon Co_PI: Dr.SK Shankar, Prof & head, HBTR, Department of Neuropathology, NIMHANS, Bangalore
20	Expression of GDNF receptors is preserved in nigral dopaminergic neurons of normally aging humans. PI: Dr. Alladi Phalguni Anand, Department of Neurophysiology, NIMHANS, Bangalore Co-PI: Dr.Anita Mahadevan, Dr. S.K.Shankar, HBTR, Department of Neuropathology, NIMHANS, Bangalore
21	Idiopathic Epilepsy Syndrome – Gene locus in chromosome 3q13.3-q21 and patient specific mutation in calcium sensing Receptor gene. PI: Dr.Anuranjan Anand, Molecular Biology and Genetics Unit, JNCASR, Bangalore Co-PI: Prof P.Satishchandra, Department of Neurology, NIMHANS and Dr.SK Shankar, HBTR, Department of neuropathology, NIMHANS, Bangalore.
22	Role of lipid – protein complexes in signal transduction in brain. PI: Dr.Preethi Joshi, Department of Biophysics, NIMHANS
23	Proteomic studies of rabies viral encephalitis Collaboration with Institute of Bioinformatics with HBTR, NIMHANS, Bangalore

Publications

S. No	Name and Details
1	Ravindranath V, Bhamre S, Bhagwat SV, Anandatheertha HK, Shankar SK, Tirumalai PS. Xenobiotic metabolism in brain. Toxicology Letters 1995; 82/83, 633-638.
2	Bhamre S, Bhagwat SV, Shankar SK, Boyd MR, Ravindranath V. Flavin containing monooxygenase mediated metabolism of psychoactive drugs by human brain microsomes. Brain Research 1995; 672: 276-280.
3	Bhagwat SV, Leelevathi BC, Shankar SK, Boyd MR, Ravindranath V. Cytochrome P450 and associated monooxygenase activities in the rat and human spinal cord: Induction, immunological characterisation and immunocytochemical localization. Neuroscience 1995, 68: 593-601
4	Anita Desai, Shankar SK, Ravi V, Chandramukhi A, Gourie-Devi M. Japanese encephalitis viral antigen in the human brain and its topographic distribution. Acta Neuropathologica 1995, 89: 368-373.
5	Lalitha Shankar, Shankar SK, Vani Santosh, Taly AB, Nagaraj D, Gourie-Devi M, Satishchandra P, Swamy HS, Sarla Das. Light and ultrastructural pathology of spinal cord in sporadic forms of amyotropic lateral sclerosis from South India. Neurology India 1995, 43: 83-90.
6	Lalitha Shankar, Shankar SK, Yasha TC, Santosh V, Das S. Neuropathology and immunohistochemical study in Parkinson’s disease – a report of two cases. Neurology India 1995, 43: 154-157.
7	Bhagwat SV, Bhamre S, Boyd MR, Ravindranath V. Cerebral metabolism of imipramine and a purified flavin – containing monooxygenase from human brain. Neuropsychopharmacology 1996, 15/2: 133-142.
8	Khanna N, Shankar SK, Chandramukhi A, Jagannath C. immunohistochemical study of human groEL stress-protein in human nervous system, Indian Journal of Medical Research, 1996; 103: 103-111.
9	Satishchandra P, Sharma P, Chatterji S, Shankar SK. Psychiatric manifestations of Creutzfeldt Jacob disease; probable neuropathologic correlates. Neurology India 1996; 44: 43-46.
10	Yasha TC, Shankar L, Santosh V, Das S, Shankar SK. Histopathological and immunohistochemical evaluation of ageing changes in normal human brain; Indian Journal of Medical Research, 1997,105: 141-150.
11	Satishchandra P, Yasha T, Lalitha Shankar, Vani Santosh, Sarla Das, Swamy HS, Shankar SK. Familial Alzheimer’s disease – first report from India. Alzheimer’s Disease and Associated Disorders 1997; 11: 107-109.
12	Minassain BA, Jeffery R Lee, Herbrick J, Huizenga J, Soder S, Mungall AJ, Dunham I, Gardner R, Fong CG, Carpenter S, Jardim L, Satischandra P, Andermann E, Cartersnead III O, Lopes-Cendes I, Tsui LC, Delgado Escueta AV, Rouleau GA, Scherer SW. Mutations in gene encoding a novel protein tyrosine phosphatase cause progressive myoclonic epilepsy, Nature Genetics, 1998; 20: 171-174.
13	Jagdeesh SR, Subhash MN. Effect of antidepressants on intracellular Ca ++ mobilization in human frontal cortex. Biological Psychiatry, 1998; 44: 617-621.
14	Muthane U, Yasha TC, Shankar SK. Low numbers and no loss of melanised nigral neurons with increasing age in normal human brains from India; Annals of Neurology 1998, 43: 283-287.
15	Shankar SK, Anita Mahadevan. Relevance of Human Brain Banking in Neuroscience – A National Facility. Annals of Indian Academy of Neurology 1999; 2: 59-78.
16	Jagannatha Rao KS, Shanmughavelu P, Shankar SK, Rukmini Devi RP, Rao RV, Pandey S, Menon RB. Trace elements interrelationship in cerebrospinal fluid of normal and Alzheimer’s disease. Alzheimer’s Report 1999; 2:333-338.
17	Shankar SK, Gourie – Devi M, Lalitha Shankar, Yasha TC, Vani Santosh, Sarla Das. Pathology of Madras type of motor neuron disease (MMND) – a histological and immunohistochemical study. Acta Neuropathologica 2000; 99: 428-434.
18	Satishchandra P, Nalini A, Gourie-Devi M, Neelam Khanna, Vani Santosh, Ravi V, Anita Desai, Chandramukhi A, Jaykumar PN, Shankar SK . Profile of neurologic disorders associated with HIV/AIDS from Bangalore, India (1989-1996). Indian Journal of Medical Research 2000; 111: 14-23.
19	Bhagwat SV, Boyd MR, Ravindranath V. Multiple forms of Cytochrome P 450 and associated monooxygenase activities in the human brain mitochodria. Biochemical Pharmacology 2000 59: 573-582.
20	SC Upadhya, PS Tirumalai, MR Boyd, T Mori, V Ravindranath. Cytochrome P4502e (Cyp2e) in brain: Constitutive expression, induction by ethanol and localisation by Fluorescent insitu hybridisation, Archives of Biophysics Biochemistry 2000; 373: 23-34.
21	Savitha K, Santosh V, Shareef MM, Shankar SK, Christopher R, Shetty KT. Expression of p67 (MUNC-18) in adult human brain and neuroectodermal tumors of human central nervous system. Acta Neuropathologica 2000; 99:191-198.
22	Swamy HS, Madhusudhana SN, Shankar SK.. Rabies and antirabies vaccination – A clinicopathological appraisal and management. In: Progress in Clinical Neurosciences, S. Venkataraman, S.Kumaravelu (eds). Mediworld Publication, New Delhi, 1997, pp369.
23	Desai A, Shankar SK, Jayakumar PN, Chandramukhi A, Gourie-Devi M, Ravikumar BV, Ravi V. Co-Existence of cerebral cysticercosis with Japanese Encephalitis – A prognostic modulator. Epidemiology Infection 1997; 118: 165.
24	Shankar SK, Yasha TC, Vani Santosh. Pathobiology of Prion disease-link between CJD-Kuru-Scrapie and BSE (Mad cow disease). In: Recent Advances in Pathology, U.L.Wagholikar, K.P.Deodhar (eds.), Jay Pee Brothers Publisher Ltd., New Delhi 1998, pp150.
25	Satishchandra P, Ullal UR, Shankar SK. Hot water Epilepsy in reflex epilepsies and reflex seizures. In: Advances in Neurology (72): B.G.Zifkin, F.Abderman, A.Ceumanoir, A.J.Rowan (eds.), Lippincott-Raven Publishers, Philadelphia, USA 1998, pp283.
26	S Balijepalli, MR Boyd, V Ravindranath. Human brain Thiol transferase: Constitutive expression and localisation by Fluorescence insitu hybridisation. Mol Brain Res. 2000 Dec 28; 85(1-2): 123-32.
27	Mahadevan A, Gayathri N, Taly AB, Santosh V, Yasha TC, Shankar SK. Vasculitic neuropathy in HIV infection: a clinicopathological study. Neurol India. 2001 Sep;49(3):277-83.
28	Khanna N, Chandramuki A, Desai A, Ravi V, Santosh V, Shankar SK, Satishchandra P. Cryptococcosis in the immunocompromised host with special reference to AIDS. Indian J Chest Dis Allied Sci. 2000 Oct-Dec;42(4):311-5.
29	SJ Chinta, H Pai, Sudarshan C, Upadhya, MR Boyd, V Ravindranath. Constitutive expression and localisation of major drug metabolising enzyme Cytochrome P 4502D in human brain. Mol Brain Res. 2002 Jun 30; 103(1-2) : 49-61.
30	Mahadevan A, Shankar SK, Yasha TC, Santosh V, Sarkar C, Desai AP, Satishchandra P. Brain biopsy in Creutzfeldt-Jakob disease: evolution of pathological changes by prion protein immunohistochemistry. Neuropathol Appl Neurobiol. 2002 Aug;28(4):314-24.
31	Sougata Saha and P N Rangarajan (2003) Common host genes are activated in mouse brain by Japanese Encephalitis and Rabies viruses. J.Gen. Virol. (in press).
32	Pai HV, Upadhya SC, Chinta SJ, Hegde SN, Ravindranath V. Differential metabolism of alprazolam by liver and brain cytochrome(P4503A) to pharmacologically active metabolite. Pharmacogenesis. J. 2002; 2(4): 243-58.
33	Shankar SK, A Mahadevan. Human Brain Bank at NIMHANS. Current Science, Vol.83, No.5:544-545, September 2002.
34	Chandramuki A, Lyashchenko K, Kumari HB, Khanna N, Brusasca P, Gourie-Devi M, Satishchandra P, Shankar SK, Ravi V, Alcabes P, Kanaujia GV, Gennaro ML. Detection of antibody to Mycobacterium tuberculosis protein antigens in the cerebrospinal fluid of patients with tuberculous meningitis. J Infect Dis. 2002 Sep 1;186(5):678-83.
35	Jayakumar PN, Srikanth SG, Chandrashekar HS, Kovoor JM, Shankar SK, Anandh B. Pyruvate: an in vivo marker of cestodal infestation of the human brain on proton MR spectroscopy. J Magn Reson Imaging. 2003 Dec;18(6):675-80.
36	Rao CR, Jain K, Bhatia K, Laksmaiah KC, Shankar SK. Association of primary central nervous system lymphomas with the Epstein-Barr virus. Neurol India. 2003 Jun;51(2):237-40.
37	Ramakrishna C, Ravi V, Desai A, Subbakrishna DK, Shankar SK, Chandramuki A. T helper responses to Japanese encephalitis virus infection are dependent on the route of inoculation and the strain of mouse used. J Gen Virol. 2003 Jun;84(Pt 6):1559-67.
38	Suja MS, Mahadevan A, Sundaram C, Mani J, Sagar BC, Hemachudha T, Wacharapluesadee S, Madhusudana SN, Shankar SK. Rabies encephalitis following fox bite--histological and immunohistochemical evaluation of lesions caused by virus. Clin Neuropathol. 2004 Nov-Dec;23(6):271-6.
39	Siddappa NB, Dash PK, Mahadevan A, Jayasuryan N, Hu F, Dice B, Keefe R, Satish KS, Satish B, Sreekanthan K, Chatterjee R, Venu K, Satishchandra P, Ravi V, Shankar SK, Shankarappa R, Ranga U. Identification of subtype C human immunodeficiency virus type 1 by subtype-specific PCR and its use in the characterization of viruses circulating in the southern parts of India. J Clin Microbiol. 2004 Jun;42(6):2742-51.
40	Sinha S, Satishchandra P, Santosh V, Gayatri N, Shankar SK. Neuronal ceroid lipofuscinosis: a clinicopathological study. Seizure. 2004 Jun;13(4):235-40.
41	Ranga U, Shankarappa R, Siddappa NB, Ramakrishna L, Nagendran R, Mahalingam M, Mahadevan A, Jayasuryan N, Satishchandra P, Shankar SK, Prasad VR. Tat protein of human immunodeficiency virus type 1 subtype C strains is a defective chemokine. J Virol. 2004 Mar;78(5):2586-90.
42	Siddappa NB, Dash PK, Mahadevan A, Desai A, Jayasuryan N, Ravi V, Satishchandra P, Shankar SK, Ranga U. Identification of unique B/C recombinant strains of HIV-1 in the southern state of Karnataka, India. AIDS. 2005 Sep2;19(13):1426-9.
43	Shankar SK, Mahadevan A, Satishchandra P, Kumar RU, Yasha TC, Santosh V, Chandramuki A, Ravi V, Nath A. Neuropathology of HIV/AIDS with an overview of the Indian scene. Indian J Med Res. 2005 Apr;121(4):468-88.
44	Gupta VB, Anitha S, Hegde ML, Zecca L, Garruto RM, Ravid R, Shankar SK, Stein R, Shanmugavelu P, Jagannatha Rao KS. Aluminium in Alzheimer's disease: are we still at a crossroad? Cell Mol Life Sci. 2005 Jan;62(2):143-58.
45	Ullal GR, Satishchandra P, Kalladka D, Rajashekar K, Archana K, Mahadevan A, Shankar SK. Kindling & mossy fibre sprouting in the rat hippocampus following hot water induced hyperthermic seizures. Indian J Med Res. 2006 Sep;124(3):331-42.
46	Rani SB, Mahadevan A, Anilkumar SR, Raju TR, Shankar SK. Expression of nestin--a stem cell associated intermediate filament in human CNS tumours. Indian J Med Res. 2006 Sep;124(3):269-80.
47	Mahadevan A, Satishchandra P, Prachet KK, Sidappa NB, Ranga U, Santosh V, Yasha TC, Desai A, Ravi V, Shankar SK. Optic nerve axonal pathology is related to abnormal visual evoked responses in AIDS. Acta Neuropathol. 2006 Oct;112(4):461-9.
48	Muthane UB, Chickabasaviah YT, Henderson J, Kingsbury AE, Kilford L, Shankar SK, Subbakrishna DK, Lees AJ. Melanized nigral neuronal numbers in Nigerian and British individuals. Mov Disord. 2006 Aug;21(8):1239-41.
49	Hegde ML, Gupta VB, Anitha M, Harikrishna T, Shankar SK, Muthane U, Subba Rao K, Jagannatha Rao KS. Studies on genomic DNA topology and stability in brain regions of Parkinson's disease. Arch Biochem Biophys. 2006 May 15;449(1-2):143-56.
50	Siddappa NB, Kashi VP, Venkatramanan M, Balasiddaiah A, Jayasuryan N,Mahadevan A, Desai A, Satish KS, Shankar SK, Ravi V, Ranga U. Gene expression analysis from human immunodeficiency virus type 1 subtype C promoter and construction of bicistronic reporter vectors. AIDS Res Hum Retroviruses. 2007 Oct;23(10):1268-78
51	Satishchandra P, Mathew T, Gadre G, Nagarathna S, Chandramukhi A, Mahadevan A, Shankar SK. Cryptococcal meningitis: clinical, diagnostic and therapeutic overviews. Neurol India. 2007 Jul-Sep;55(3):226-32.
52	Shankar SK, Mahadevan A, Sundaram C, Sarkar C, Chacko G, Lanjewar DN, Santosh V, Yasha TC, Radhakrishnan VV. Pathobiology of fungal infections of the central nervous system with special reference to the Indian scenario. Neurol India. 2007 Jul-Sep;55(3):198-215.
53	Shukla D, Mahadevan A, Sastry KV, Shankar SK. Pathology of post traumatic brainstem and hypothalamic injuries. Clin Neuropathol. 2007 Sep-Oct;26(5):197-209.
54	Christopher R, Nagaraja D, Shankar SK. Homocysteine and cerebral stroke in developing countries. Curr Med Chem. 2007;14(22):2393-401.
55	Sundar P, Mahadevan A, Jayshree RS, Subbakrishna DK, Shankar SK. Toxoplasma seroprevalence in healthy voluntary blood donors from urban Karnataka. Indian J Med Res. 2007 Jul;126(1):50-5.
56	Mahadevan A, Shankar SK, Satishchandra P, Ranga U, Chickabasaviah YT, Santosh V, Vasanthapuram R, Pardo CA, Nath A, Zink MC. Characterization of human immunodeficiency virus (HIV)-infected cells in infiltrates associated with CNS opportunistic infections in patients with HIV clade C infection. J Neuropathol Exp Neurol. 2007 Sep;66(9):799-808.
57	Sinha S, Satishchandra P, Gayathri N, Yasha TC, Shankar SK. Progressive myoclonic epilepsy: A clinical, electrophysiological and pathological study from South India. J Neurol Sci. 2007 Jan 15;252(1):16-23.
58	Kapoor A, Satishchandra P, Ratnapriya R, Reddy R, Kadandale J, Shankar SK, Anand A. An idiopathic epilepsy syndrome linked to 3q13.3-q21 and missense mutations in the extracellular calcium sensing receptor gene. Ann Neurol. 2008 Aug;64(2):158-67.
59	Mahadevan A, Vaidya SR, Wairagkar NS, Khedekar D, Kovoor JM, Santosh V, Yasha TC, Satishchandra P, Ravi V, Shankar SK. Case of fulminant-SSPE associated with measles genotype D7 from India: an autopsy study. Neuropathology. 2008 Dec;28(6):621-6.
60	Dash PK, Siddappa NB, Mangaiarkarasi A, Mahendarkar AV, Roshan P, Anand KK, Mahadevan A, Satishchandra P, Shankar SK, Prasad VR, Ranga U. Exceptional molecular and coreceptor-requirement properties of molecular clones isolated from an Human Immunodeficiency Virus Type-1 subtype C infection. Retrovirology. 2008 Mar 7;5:25.
61	Shankar SK, Mahadevan A, Kovoor JM. Neuropathology of viral infections of the central nervous system. Neuroimaging Clin N Am. 2008 Feb;18(1):19-39; vii.
62	Singh S, Satishchandra P, Shankar SK, Ganesh S. Lafora disease in the Indian population: EPM2A and NHLRC1 gene mutations and their impact on subcellular localization of laforin and malin. Hum Mutat. 2008 Jun;29(6):E1-12.
63	Meenakshi-Sundaram S, Mahadevan A, Taly AB, Arunodaya GR, Swamy HS, Shankar SK. Wilson's disease: a clinico-neuropathological autopsy study. J Clin Neurosci.2008 Apr;15(4):409-17.
64	Kher M, Rao MY, Acharya PT, Mahadevan A, Shankar SK. Heidenhain variant of Creutzfeldt-Jakob disease: An autopsy study from India. Ann Indian Acad Neurol.2009 Jan;12(1):48-51.
65	Gadre G, Satishchandra P, Mahadevan A, Suja M, Madhusudana S, Sundaram C, Shankar S. Rabies viral encephalitis - clinical determinants in diagnosis with special reference to paralytic form. J Neurol Neurosurg Psychiatry. 2009
66	Bhattacharyya S, Khanna S, Chakrabarty K, Mahadevan A, Christopher R, Shankar SK. Anti-brain autoantibodies and altered excitatory neurotransmitters in obsessive-compulsive disorder. Neuropsychopharmacology. 2009 Nov;34(12):2489-96.
67	Chakraborti S, Mahadevan A, Govindan A, Nagarathna S, Santosh V, Yasha TC, Devi BI, Chandramouli BA, Kovoor JM, Chandramuki A, Shankar SK. Clinicopathological study of tuberculous brain abscess. Pathol Res Pract. 2009;205(12):815-22.
68	Bharatkumar VP, Nagaraja D, Shankar SK, Christopher R. Hyperhomocysteinemia and MTHFR C677T homozygosity in a vegetarian male with sinovenous thrombosis of the brain. J Clin Neurosci. 2009 Oct;16(10):1380-1.
69	Suja MS, Mahadevan A, Madhusudhana SN, Vijayasarathi SK, Shankar SK. Neuroanatomical mapping of rabies nucleocapsid viral antigen distribution and apoptosis in pathogenesis in street dog rabies--an immunohistochemical study. Clin Neuropathol. 2009 Mar-pr;28(2):113-24.
70	De Silva KR, Shankar SK, Mahadevan A, Dodd PR. A brain bank for Sri Lanka. Ceylon Med J. 2008 Dec;53(4):139-40.
71	Alladi PA, Mahadevan A, Yasha TC, Raju TR, Shankar SK, Muthane U. Absence of age-related changes in nigral dopaminergic neurons of Asian Indians: relevance to lower incidence of Parkinson's disease. Neuroscience. 2009 Mar 3;159(1):236-45.
72	Li W, Huang Y, Reid R, Steiner J, Malpica-Llanos T, Darden TA, Shankar SK,Mahadevan A, Satishchandra P, Nath A. NMDA receptor activation by HIV-Tat protein is clade dependent. J Neurosci. 2008 Nov 19;28(47):12190-8.
73	Alladi PA, Mahadevan A, Shankar SK, Raju TR, Muthane U. Expression of GDNF receptors GFRalpha1 and RET is preserved in substantia nigra pars compacta of aging Asian Indians. J Chem Neuroanat. 2010 Mar 25. [Epub ahead of print] PubMed
74	Rafi W, Chandramuki A, Mani R, Satishchandra P, Shankar SK. Rapid diagnosis of acute bacterial meningitis: role of a broad range 16S rRNA polymerase chain reaction. J Emerg Med. 2010 Feb;38(2):225-30.
75	Prashanth LK, Sinha S, Taly AB, Mahadevan A, Vasudev MK, Shankar SK. Spectrum of epilepsy in Wilson’s disease with electroencephalographic, MR imaging and pathological correlates. J Neurol Sci. Netherlands; 2010 Apr;291(1-2):44–51.
76	Kumar GGS, Mahadevan A, Guruprasad AS, Kovoor JME, Satishchandra P, Nath A, Ranga U, Shankar SK. Eccentric target sign in cerebral toxoplasmosis: neuropathological correlate to the imaging feature. J MagnReson Imaging. United States; 2010 Jun; 31(6):1469–72.
77	Gadre G, Satishchandra P, Mahadevan A, Suja MS, Madhusudana SN, Sundaram C, Shankar SK. Rabies viral encephalitis: clinical determinants in diagnosis with special reference to paralytic form. J NeurolNeurosurg Psychiatry. England; 2010Jul;81(7):812–20.
78	Adurthi S, Mahadevan A, Bantwal R, Satishchandra P, Ramprasad S, Sridhar H, Shankar SK, Nath A, Jayshree RS. Utility of molecular and serodiagnostic tools in cerebral toxoplasmosis with and without tuberculous meningitis in AIDS patients: A study from South India. Ann Indian Acad Neurol. India; 2010 Oct;13(4):263–70.
79	Sinha S, Satishchandra P, Mahadevan A, Bhimani BC, Kovur JME, Shankar SK. Fatal status epilepticus: a clinico-pathological analysis among 100 patients: from a developing country perspective. Epilepsy Res. Netherlands; 2010 Oct;91(2-3):193–204.
80	Alladi PA, Mahadevan A, Shankar SK, Raju TR, Muthane U. Expression of GDNF receptors GFRalpha1 and RET is preserved in substantia nigra pars compacta of aging Asian Indians. J ChemNeuroanat. Netherlands; 2010 Sep;40(1):43–52.
81	Alladi PA, Mahadevan A, Vijayalakshmi K, Muthane U, Shankar SK, Raju TR. Ageing enhances alpha-synuclein, ubiquitin and endoplasmic reticular stress protein expression in the nigral neurons of Asian Indians. Neurochem Int. England; 2010 Nov;57(5):530–9.
82	Rao SNR, Maity R, Sharma J, Dey P, Shankar SK, Satishchandra P,Jana NR. Sequestration of chaperones and proteasome into Lafora bodies and proteasomal dysfunction induced by Lafora disease-associated mutations of malin. Hum Mol Genet. England; 2010 Dec;19(23):4726–34.
83	Kulkarni GB, Mahadevan A, Taly AB, Nalini A, Shankar SK. Sural nerve biopsy in chronic inflammatory demyelinating polyneuropathy: are supportive pathologic criteria useful in diagnosis? Neurol India. India; 2010;58(4):542–8.
84	Shankar SK. Biology of aging brain. Indian J PatholMicrobiol. India; 2010;53(4):595–604.
85	Pruthi N, Chandramouli BA, Kuttappa TB, Rao SL, Subbakrishna DK, Abraham MP, et al. Apolipoprotein E polymorphism and outcome after mild to moderate traumatic brain injury: a study of patient population in India. Neurol India. India; 2010;58(2):264–9.
86	Adurthi S, Mahadevan A, Bantwal R, Satishchandra P, Ramprasad S, Sridhar H, Shankar SK, Nath A, Jayshree RS. Diagnosis of cerebral toxoplasmosis. Ann Indian Acad Neurol. India; 2011 Apr;14(2):145–6.
87	Wairagkar N, Chowdhury D, Vaidya S, Sikchi S, Shaikh N, Hungund L, Tomar RS, Biswas D, Yadav K, Mahanta J, Das VN, Yergolkar P, Gunasekaran P, Raja D, Jadi R, Ramamurty N, Mishra AC, Arun K, Biswas AK, Bag B, Debberma S, Dhole TN, De S, Das PK, Dwibedi B, Gupta SN, Illankumar M, Jampa L, Ketkar A, Kumar N, Kumar R, Khobragade P, Kadri SM, Mahadevan A, Murhekar M, Gupte MD, Martolia H, Mazi D, Ratho RK, Shankar SK, Slathia S, Sugunan AP, Vittal CS, Vijaykumar G,Vashishtha VM. Molecular epidemiology of measles in India, 2005-2010. J Infect Dis. United States; 2011 Jul; 204Suppl :S403–13.
88	Reddy GBM, Singh R, Singh RP, Singh KP, Gupta PK, Mahadevan A, Shankar SK, Ramakrishnan MA, Verma R. Molecular characterization of Indian rabies virus isolates by partial sequencing of nucleoprotein (N) and phosphoprotein (P) genes. Virus Genes. United States; 2011 Aug;43(1):13–7.
89	Mythri RB, Venkateshappa C, Harish G, Mahadevan A, Muthane UB, Yasha TC, Srinivas Bharath MM, Shankar SK. Evaluation of markers of oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson’s disease brains. Neurochem Res. United States; 2011 Aug;36(8):1452–63.
90	Shankar SK, Kumar SKP, Mulimani VH. Calcium alginate entrapped preparation of alpha-galactosidase: its stability and application in hydrolysis of soymilk galactooligosaccharides. J IndMicrobiolBiotechnol. England; 2011 Sep;38(9):1399–405.
91	Sharma J, Rao SNR, Shankar SK, Satishchandra P, Jana NR. Lafora disease ubiquitin ligase malin promotes proteasomal degradation of neuronatin and regulates glycogen synthesis. Neurobiol Dis. United States; 2011 Oct;44(1):133–41.
92	Harish G, Venkateshappa C, Mahadevan A, Pruthi N, Bharath MMS, Shankar SK. Effect of storage time, postmortem interval, agonal state, and gender on the postmortem preservation of glial fibrillary acidic protein and oxidatively damaged proteins in human brains. Biopreserv Biobank. United States; 2011 Dec;9(4):379–87.
93	Harish G, Venkateshappa C, Mahadevan A, Pruthi N, Srinivas Bharath MM, Shankar SK. Glutathione metabolismis modulated by postmortem interval, gender difference and agonal state in postmortem human brains. Neurochem Int. England; 2011 Dec;59(7):1029–42.
94	Shankar SK. Human umbilical cord blood-derived mesenchymal stem cells and their effect on gliomas. Neurology India. India; 2011. p. 226–8.
95	Suja MS, Mahadevan A, Madhusudana SN, Shankar SK. Role of apoptosis in rabies viral encephalitis: a comparative study in mice, canine, and human brain with a review of literature. Patholog Res Int. United States; 2011;2011:374286.
96	Sundaram C, Shankar SK, Thong WK, Pardo-Villamizar CA. Pathology and diagnosis of central nervous system infections. Patholog Res Int. United States; 2011;2011:878263.
97	Sameer Kumar G S, Abhilash KV, Lakshmi Devi N S, Marimuthy A, Shivakumar K, Swapnali P, Jyoti B D, Pramila T, Ramesh H, Keshava Prasad T S, Harsha H C, Ramachandra Y L, Mahadevan A, Ragothama C, Shankar S K, Akhilesh P. Gene Expression Profiling of Tuberculous Meningitis. J Proteomics Bioinform. 2011;4(5):98–105.
98	Venugopal AK, Sameer Kumar GS, Mahadevan A, Selvan LDN, Marimuthu A, Dikshit JB, Tata P, Ramachandra Y, Chaerkady R, Sinha S, ChandramouliB,Arivazhagan A, Satishchandra P, Shankar SK, Pandey A. Transcriptomic Profiling of Medial Temporal Lobe Epilepsy. J Proteomics Bioinform. 2012 Jan;5(2).
99	Venkateshappa C, Harish G, Mythri RB, Mahadevan A, Bharath MMS, Shankar SK. Increased oxidative damage and decreased antioxidant function in aging human substantia nigra compared to striatum: implications for Parkinson’s disease. Neurochem Res. United States; 2012 Feb;37(2):358–69.
100	Pundir AS, Hameed LS, Dikshit PC, Kumar P, Mohan S, Radotra B, Shankar SK, Mahadevan A, Iyengar S. Expression of medium and heavy chain neurofilamentsin the developing human auditory cortex. Brain StructFunct. Germany; 2012 Apr;217(2):303–21.
101	Jadav R, Sinha S, Nagarathna S, Bindu P, Mahadevan A, Bharath R, Shankar S, Taly A. Carcinomatous meningitis: Yet another cause for rapidly progressive dementia and triphasic waves in electroencephalograph!. J Neurosci Rural Pract. India; 2012 May;3(2):207–9.
102	Shankar SK, Mahadevan A, Sapico SD, Ghodkirekar MSG, Pinto RGW, Madhusudana SN. Rabies viral encephalitis with proable 25 year incubation period!. Ann Indian Acad Neurol. India; 2012 Jul;15(3):221–3.
103	Venkateshappa C, Harish G, Mahadevan A, Srinivas Bharath MM, Shankar SK. Elevated oxidative stress and decreased antioxidant function in the human hippocampus and frontal cortex with increasing age: implications for neurodegeneration in Alzheimer’s disease. Neurochem Res. United States; 2012 Aug;37(8):1601–14.
104	Wong KT, Ng KY, Ong KC, Ng WF, Shankar SK, Mahadevan A,Radotra B, Su IJ, Lau G, Ling AE, Chan KP, Macorelles P, Vallet S, Cardosa MJ, Desai A, Ravi V, Nagata N, Shimizu H, Takasaki T. Enterovirus 71 encephalomyelitis and Japanese encephalitis can be distinguished by topographic distribution of inflammation and specific intraneuronal detection of viral antigen and RNA. Neuropathol Appl Neurobiol. England; 2012 Aug;38(5):443–53.
105	Bachu M, Mukthey AB, Murali R V, Cheedarla N, Mahadevan A, Shankar SK, Satish KS, Kundu TK, Ranga U. Sequence insertions in the HIV type 1 subtype C viral promoter predominantly generate an additional NF-kappaB binding site. AIDS Res Hum Retroviruses. United States; 2012 Oct;28(10):1362–8.
106	Chakraborti S, Mahadevan A, Govindan A, Bhateja A, Dwarakanath S, Aravinda HR, Phalguni AA, Santosh V, Yasha TC, Rout P, Sampath S, Shankar SK. Rosette- forming glioneuronal tumor -- evidence of stem cell origin with biphenotypic differentiation. Virchows Arch. Germany; 2012 Nov;461(5):581–8.
107	Bachu M, Yalla S, Asokan M, Verma A, Neogi U, Sharma S, Murali RV, Mukthey AB, Bhatt R, Chatterjee S, Rajan RE, Cheedarla N, Yadavalli VS, Mahadevan A, Shankar SK et al. Multiple NF-kappaB sites in HIV-1 subtype C long terminal repeat confer superior magnitude of transcription and thereby the enhanced viral predominance.J Biol Chem. United States; 2012 Dec;287(53):44714–35.
108	Jethwani DP, Mahadevan A, Ramamurthy BS, Mangala R, Shankar SK. Septo-optic dysplasia: an autopsy study of a 23-week fetus. ClinNeuropathol. Germany; 2012;31(1):44–50.
109	Kumar GSS, Venugopal AK, Mahadevan A, Renuse S, Harsha HC, Sahasrabuddhe NA, Pawar H, Sharma R, Kumar P, Rajagopalan S, Waddell K,Ramachandra YL, Satishchandra P, Chaerkady R, Prasad TS, Shankar SK, Pandey A. Quantitative proteomics for identifying biomarkers for tuberculous meningitis. Clin Proteomics. England; 2012;9(1):12.
110	Shankar S K, Mahadevan A. Biobanking for cancer research: Preservation of tissue integrity – Some technical considerations. Ind Jour Neurosurg. 2012;1(2):130–8.
111	Harish G, Mahadevan A, Srinivas Bharath MM, Shankar SK. Alteration in glutathione content and associated enzyme activities in the synaptic terminals but not in the non- synaptic mitochondria from the frontal cortex of Parkinson’s disease brains. Neurochem Res. United States; 2013 Jan;38(1):186–200.
112	Kannangai R, Sachithanandham J, Mahadevan A, Abraham AM, Sridharan G, Desai A, Ravi V, Shankar SK. Association of neurotropic viruses in HIV-infected individuals who died of secondary complications of tuberculosis, cryptococcosis, or toxoplasmosis in South India. J ClinMicrobiol. United States; 2013 Mar; 51(3):1022–5.
113	Sharma J, Mukherjee D, Rao SN, Iyengar S, Shankar SK, Satishchandra P, Jana NR.. Neuronatin-mediated aberrant calcium signaling and endoplasmic reticulum stress underlie neuropathology in Lafora disease. J Biol Chem. United States; 2013 Mar;288(13):9482–90.
114	Harish G, Venkateshappa C, Mahadevan A, Pruthi N, Bharath MMS, Shankar SK. Mitochondrial function in human brains is affected by pre- and post mortem factors. NeuropatholApplNeurobiol. England; 2013 Apr;39(3):298–315.
115	Netravathi M, Mahadevan A, Satishchandra P, Shobha N, Mailankody P, Kandavel T, Jitender S, Anantaram G, Nagarathna S, Govekar S, Ravikumar BV Ravi V, Shankar SK. Progressive multifocal leukoencephalopathy (PML) associated with HIV Clade C--is not uncommon. J Neurovirol. United States; 2013 Jun;19(3):198–208.
116	Nagappa M, Taly AB, Sinha S, Bharath RD, Mahadevan A, Bindu PS, Saini JS, Prasad C, Shankar SK. Tumefactive demyelination: clinical, imaging and follow-up observations in thirty-nine patients. ActaNeurol Scand. Denmark; 2013 Jul;128(1):39–47.
117	Shyambabu C, Satishchandra P, Mahadevan A, Pillai Shibu V, Ravishankar S, Sidappa N, Udaykumar R, Ravi V, Shankar SK. Usefulness of stereotactic biopsy and neuroimaging in management of HIV-1 Clade C associated focal brain lesions with special focus on cerebral toxoplasmosis. ClinNeurolNeurosurg. Netherlands; 2013 Jul;115(7):995–1002.
118	Mahadevan A, Ramalingaiah AH, Parthasarathy S, Nath A, Ranga U, Krishna SS. Neuropathological correlate of the ‘concentric target sign’ in MRI of HIV-associated cerebral toxoplasmosis. J MagnReson Imaging. United States; 2013 Aug;38(2):488–95.
119	Dhiman V, Rao S, Sinha S, Arimappamagan A, Mahadevan A, Bharath RD, Saini J, Jamuna R, Keshav Kumar J, Rao SL, Chandramouli BA, Satishchandra P, Shankar SK. Outcome of lesionectomy in medically refractory epilepsy due to non-mesial temporal sclerosis(non-MTS) lesions. ClinNeurol Neurosurg.Netherlands; 2013 Dec;115(12):2445–53.
120	Venugopal AK, Ghantasala SSK, Selvan LDN, Mahadevan A, Renuse S, Kumar P, Pawar H, Sahasrabhuddhe NA, Suja MS, Ramachandra YL, Prasad TS, Madhusudhana SN, Hc H, Chaerkady R, Satishchandra P, Pandey A, Shankar SK. Quantitative proteomics for identifying biomarkers for Rabies. Clin Proteomics. England; 2013;10(1):3.
121	Mangalore S, Desai S, Mahadevan A, Kovoor JME, Vasudev LMK, Tally AB, Shankar SK. Cerebral tubercular thrombophlebitis presenting as venous infarct: Magnetic resonance imaging and pathologic correlation. Ann Indian Acad Neurol. India; 2014 Jan;17(1):130–4.
122	Wang C, Klechikov AG, Gharibyan AL, Warmlander SKTS, Jarvet J, Zhao L, Jia X, Narayana VK, Shankar SK, Olofsson A, Brännström T, Mu Y, Gräslund A,Morozova-Roche LA. The role of pro-inflammatory S100A9 in Alzheimer’s disease amyloid-neuroinflammatory cascade. ActaNeuropathol. Germany; 2014 Apr;127(4):507–22.
123	Kim M-S, Pinto SM, Getnet D, Nirujogi RS, Manda SS, Chaerkady R, Madugundu AK, Kelkar DS, Isserlin R, Jain S, Thomas JK, Muthusamy B, Leal-Rojas P, Kumar P, Sahasrabuddhe NA, Balakrishnan L, Advani J, George B, Renuse S, Selvan LD, Patil AH, Nanjappa V, Radhakrishnan A, Prasad S, Subbannayya T, Raju R, Kumar M, Sreenivasamurthy SK, Marimuthu A, Sathe GJ, Chavan S, Datta KK, Subbannayya Y, Sahu A, Yelamanchi SD, Jayaram S, Rajagopalan P, Sharma J, Murthy KR, Syed N, Goel R, Khan AA, Ahmad S, Dey G, Mudgal K, Chatterjee A, Huang TC, Zhong J, Wu X, Shaw PG, Freed D, Zahari MS, Mukherjee KK, Shankar SK et al. A draft map of the human proteome. Nature. England; 2014 May;509(7502):575–81.
124	Savitr Sastri B V, Arivazhagan A, Sinha S, Mahadevan A, Bharath RD, Saini J, Jamuna R, Kumar JK, Rao SL, Chandramouli BA, Shankar SK ,Satishchandra P. Clinico-pathological factors influencing surgical outcome in drug resistant epilepsy secondary to mesial temporal sclerosis. J Neurol Sci. Netherlands; 2014 May;340(1-2):183–90.
125	Thounaojam MC, Kundu K, Kaushik DK, Swaroop S, Mahadevan A, Shankar SK, Basu A. MicroRNA 155 regulates Japanese encephalitis virus-induced inflammatory response by targeting Src homology 2-containing inositol phosphatase 1. J Virol. United States; 2014 May;88(9):4798–810.
126	Chikkannaiah P, Mahadevan A, Gosavi M, Kangle R, Anuradha, Shankar SK. Sirenomelia with associated systemic anomalies: an autopsy pathologic illustration of a series of four cases. Pathol Res Pract. Germany; 2014 Jul;210(7):444–9.
127	Nazmi A, Mukherjee S, Kundu K, Dutta K, Mahadevan A, Shankar SK, Basu A. TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection. Neurobiol Dis. United States; 2014 Sep;69:235–47.
128	Pradeep K, Sinha S, Saini J, Mahadevan A, Arivazhagan A, Bharath RD, Bindu PS, Jamuna R, Rao MB, Chandramouli BA, Shankar SK, Satishchandra P. Evolution of MRI changes in Rasmussen’s encephalitis. ActaNeurol Scand. Denmark; 2014 Oct;130(4):253–9.
129	Mani RS, Madhusudana SN, Mahadevan A, Reddy V, Belludi AY, Shankar SK. Utility of real-time Taqman PCR for antemortem and postmortem diagnosis of human rabies. J Med Virol. United States; 2014 Oct;86(10):1804–12.
130	Tripathi S, Patro I, Mahadevan A, Patro N, Phillip M, Shankar SK. Glial alterations in tuberculous and cryptococcal meningitis and their relation to HIV co-infection--a study on human brains. J Infect Dev Ctries. Italy; 2014 Nov;8(11):1421–43.
131	SK Shankar, Anita Mahadevan GH and MMSB. Human Brain Tissue Repository: A National Facility Fostering Neurosciences Research. ProcNatlAcadSciIndia, Sect B BiolSci. 2014;84(2):239–50.
132	Govindan A, Mahadevan A, Chakraborti S, Furtado S, Krishna SS. Absence of anaplastic lymphoma kinase-1 expression in inflammatory myofibroblastic tumors of the central nervous system: does it signify a different nosologic entity from its systemic counterpart? Indian J PatholMicrobiol. India; 2014;57(2):178–82.
133	Sahu A, Kumar S, Sreenivasamurthy SK, Selvan LDN, Madugundu AK, Yelamanchi SD, Puttamallesh VN, Dey G, Anil AK, Srinivasan A, Mukherjee KK, Gowda H, Satishchandra P, Mahadevan A, Pandey A, Prasad TS,Shankar SK. Host response profile of human brain proteome in toxoplasma encephalitis co-infected with HIV. Clin Proteomics. England; 2014;11(1):39.
134	Dhiman V, Sinha S, Arimappamagan A, Mahadevan A, Bharath RD, Saini J, Rajeswaran J, Rao MB, Shankar SK, Satishchandra P. Predictors of spontaneous transient seizure remission in patients of medically refractory epilepsy due to mesial temporal sclerosis (MTS). Epilepsy Res. Netherlands; 2015 Feb;110: 55–61.
135	Harish G, Mahadevan A, Pruthi N, Sreenivasamurthy SK, Puttamallesh VN, Keshava Prasad TS, Shankar SK, Srinivas Bharath MM. Characterization of traumatic brain injury in human brains reveals distinct cellular and molecular changes in contusion and pericontusion. J Neurochem. England; 2015 Jul;134(1):156–72.
136	Mishra M, Varghese RK, Verma A, Das S, Aguiar RS, Tanuri A, Mahadevan A, Shankar SK, Satishchandra P, Ranga U.Genetic diversity and proviral DNA load in different neural compartments of HIV-1 subtype C infection. J Neurovirol. United States; 2015 Aug; 21(4):399–414.
137	Selvan LDN, Sreenivasamurthy SK, Kumar S, Yelamanchi SD, Madugundu AK, Anil AK, Renuse S, Nair BG, Gowda H, Mathur PP, Satishchandra P, Shankar SK. Characterization of host response to Cryptococcus neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV. MolBiosyst. England; 2015 Sep;11(9):2529–40.
138	Pundir AS, Singh UA, Ahuja N, Makhija S, Dikshit PC, Radotra B, Kumar P, Shankar SK, Mahadevan A, Roy TS, Iyengar S. Growth and refinement of excitatory synapses in the human auditory cortex. Brain StructFunct. 2015
139	Cardenas G, Guevara-Silva E, Romero F, Ugalde Y, Bonnet C, Fleury A, Sciutto E, Nunes CM, Soto-Hernández JL, Shankar SK, Mahadevan A. Spinal Taenia solium cysticercosis in Mexican and Indian patients: a comparison of 30-year experience in two neurological referral centers and review of literature. Eur spine J Off PublEur Spine SocEur Spinal Deform SocEur Sect Cerv Spine Res Soc. 2015
140	Fatima M, Kumari R, Schwamborn JC, Mahadevan A, Shankar SK, Raja R, Seth P.Tripartite containing motif 32 modulates proliferation of human neural precursor cells in HIV-1 neurodegeneration. Cell Death Differ. 2015 Nov;
141	Jyothi HJ, Vidyadhara DJ, Mahadevan A, Philip M, Parmar SK, Manohari SG, Shankar SK, Raju TR, Alladi PA. Aging causes morphological alterations in astrocytes and microglia in human substantia nigra pars compacta. Neurobiol Aging. United States; 2015 Dec; 36(12):3321–33.
142	Shankar SK. Let us promote bio-banking in India for translational research. Neurol India. India; 2015;63(5):644–6.
143	Mahadevan A, Rao CR, Shanmugham M, Shankar SK. Primary central nervous system diffuse large B-cell lymphoma in the immunocompetent: Immunophenotypic subtypes and Epstein-Barr virus association. J Neurosci Rural Pract. India; 2015 Jan;6(1):8–14.
144	Sarada Subramanian, Anita mahadevan, P Satishchandra, Shankar SK. Development of a dot blot assay with antibodies to recombinant ‘core’ 14-3-3 protein: Evaluation of its usefulness in diagnosis of creutzfeldt- Jakob disease. Ann Indian AcadNeurolAcad Neurol. 2015
145	Vijaykumar BR, Lekshmi SU, Sai Kant R, Vaigundan D, Mahadevan A, Rajendran C, Shankar SK, Jayshree RS. Genetic characterization of Toxoplasma gondii from autopsy proven cases of AIDS associated cerebral toxoplasmosis in South India. Infect Genet Evol. 2016 Jan; 39:106–12.
146	Wijesinghe P, Shankar SK, Chickabasaviah YT, Gorrie C, Amaratunga D, Hulathduwa S, Kumara KS, Samarasinghe K, Suh YH, Steinbusch HW, De Silva KR. Cytoskeletal Pathologies of Age-Related Diseases between Elderly Sri Lankan (Colombo) and Indian (Bangalore) Brain Samples. Curr Alzheimer Res. United Arab Emirates; 2016;13(3):268–8
147	Wijesinghe P, Shankar SK, Yasha TC, Gorrie C, Amaratunga D, Hulathduwa S, Kumara KS, Samarasinghe K, Suh YH, Steinbusch HW, De Silva KR. Vascular Contributions in Alzheimer’s Disease-Related Neuropathological Changes: First Autopsy Evidence from a South Asian Aging Population. J Alzheimers Dis. 2016 Sep; [Epub ahead of print].

Research Projects

S.No	Project Details
1	Is there a difference in dopaminergic neuronal number amongst normal individuals of different racial origin? Investigators: Dr.Uday Muthane, Dr.T C Yasha, Dr.SK Shankar, NIMHANS, Dr.Susan E Daniel Head, Neuropathology Research, Parkinson’s Disease Society Research Centre, Institute of Neurology, London. Funded by: Parkinson’s Disease Foundation Research Grant, Florida, USA ($35,000, 1year)
2	Degree of loss of nigral neurons following Japanese encephalitis. Possible role of Japanese encephalitis as a predisposing/causative factor for Parkinson’s disease in endemic areas. Investigators: Dr.Uday Muthane, Dr.T C Yasha, Dr.SK Shankar, NIMHANS Ginko Meckel Research Award (Rs.70,000, 1 year)
3	Cellular localisation and function of CDK 5 and P67 in the nervous system. Investigator: Dr.K.T.Shetty, Department of Neurochemistry, NIMHANS Funded by: Embassy of USA Fund (PL 480 fund) (Rs. 21,78,000)
4	Structural and biochemical basis of axonal atrophy in leprosy. Investigator: Dr.K.T.Shetty, Department of Neurochemistry, NIMHANS Funded by: Department of Science and Technology (3 years, Rs.--)
5	Expression and regulation of brain cytochrome P450 and its effect of metabolism of neurotoxin. Investigator: Dr.Vijayalakshmi Ravindranath, Department of Neurochemistry, NIMHANS Funded by: Council for Scientific and Industrial Research (Rs.6,67,000, 3 years)
6	Diagnostic potential of P67 (MUNC - 18) in neurologic disorders. Investigator: Dr.KT.Shetty, Department of Neurochemistry, NIMHANS Funded by: Indian Council for Medical Research (Rs.4,00,000, 2 years)
7	Studies of glutathione and protein thiol homeostasis in brain during oxidative stress. Investigator: Dr.Viyjayalakshmi Ravindranath, Department of Neurochemistry, NIMHANS Funded by: Indo-US Project (Rs.48,62,000, 5 years)
8	Psychoactive drug metabolism by brain cytochrome. Investigator: Dr.Vijayalakshmi Ravindranath, Department of Neurochemistry, NIMHANS Funded by: NIH, Washington DC, USA (RO-1 Project) (Rs.46,51,000, 3 years)
9	Effect of typical and atypical neuroleptics on mitochondrial electron transport chain components in mouse and human brain. Investigator: Dr.Vijayalakshmi Ravindranath, Department of Neurochemistry, NIMHANS Funded by: Theodore & Vada Stanley Foundation, USA (Rs.26,06,000, 2 years)
10	A National Survey of Creutzfeldt-Jakob disease in India Investigator: Dr.SK Shankar, Department of Neuropathology, NIMHANS Funded by: NIMHANS & Dr.Shantilal J Mehta Medical Research Foundation (Rs.35,0000, 1 year)
11	Histological and immunohistochemical study of prion reactive lesions in CJD- India Investigator: Dr.SK Shankar, Department of Neuropathology, NIMHANS Funded by: Dr.Shantilal J Mehta Medical Research Foundation (Rs.30,0000, 1 year)
12	Development of cDNA library from human brain. Investigator: Prof.C.Durga Rao, Department of Microbiology & Immunology, Indian Institute of Science, Bangalore.
13	Pharmacological characterisation of 5 HT-2 receptors and their modulation by antidepressants. Investigator: Dr.MN Subhash, Department of Neurochemistry, NIMHANS Funded by: Indian Council for Medical Research (2 years)
14	Trace elements and their interrelations in human brain. Investigators: Dr. KS Jagannath Rao, Department of Biochemistry & Nutrition, CFTRI, Mysore Funded by DST.
15	DNA Topology in Human Brain– Relevance to Neurological Disease. PI: Dr.K.S.Jagannath Rao Scientist CFTRI, Mysore/ HBTR, NIMHANS. Funded by CSIR/DBT.
16	Regional differentiation in human cerebral cortex. PI: Dr.Shuba Tole, Department of Biological Sciences, TIFR Bombay. (Funded by Senior Res. Fellow Award, Wellcome Trust, UK)
17	Study of Glutamate synthetase acitivity in CSF in cases of Chronic meningitis. PI: Dr.P.R. Krishnaswamy, Director Manipal Hospital Diagnostic Services, Manipal Hospital, Bangalore/ HBTR, NIMHANS.
18	Molecular and functional characterization of HIV-1 Long Terminal repeat (LTR) cloned from India Patients. PI: Dr. Ranga Uday Kumar, Molecular Biology and Genetics Unit, Jawaharlal Nehru center for Advanced Scientific Research, Jakkur, Bangalore/ HBTR, NIMHANS. Co-PI: Dr.SK Shankar, Prof & Head, Department of Neuropathology, NIMHANS, Bangalore Funded By: Indian Council of Medical Research.
19	Cellular tropism and viral reservoir in brain with HIV-1 Clade C virus. PI: Dr. Avindra Nath, Consultant Neurologist, Johns Hopkins School of Medicine, Baltimore, USA Co-PI: Dr.SK Shankar, Prof & Head and Dr.Anita Mahadevan, Asst Prof Department of Neuropathology, NIMHANS, Bangalore Funded By: R21 Project funded by National Institute of Neurological Diseases and Stroke (NIH) – in collaboration with Johns Hopkins School of Medicine, Baltimore, USA
20	Digitization of museum specimens PI: Dr.SK Shankar, Prof & Head, Department of Neuropathology, NIMHANS, Bangalore Co-PI: Dr.Anita Mahadevan, Asst Prof, Department of Neuropathology, NIMHANS, Bangalore Funded by: NIMHANS (Rs.1,50,000)
21	Subregional cytoarchitectural changes and cell cycle dysregulation in temporal lobe epilepsy. PI: Dr.Lily Pal, Addl Professor, Dept of Pathology, SGPGI, Lucknow Co-PI: Dr.SK Shankar, Professor, Department of Neuropathology, and Dr.P Satishchandra, Professor, Dept of Neurology, NIMHANS, Bangalore Funded by Department of Science and Technology, Govt of India
22	Genomic Proteomic and Transcriptomic Profiling of Tuberculous meningitis PI: Dr.Akhilesh Pandey, Institute of Bioinformatics, Bangalore Co-PI: Dr.SK Shankar, Dr Anita Mahadevan, Department of Neuropathology, NIMHANS, Bangalore (Funded by Department of Biootechnology, Govt of India).
23	Role of CNS opportunistic infections in development of HIV encephalitis PI: Dr. Avindra Nath, Consultant Neurologist, Johns Hopkins School of Medicine, Baltimore, USA Co-PI: Dr.SK Shankar, Prof & Head and Dr.Anita Mahadevan, Asst Prof Department of Neuropathology, NIMHANS, Bangalore. Funded By: RO1 project funded by National Institute of Neurological Diseases and Stroke (NIH), in collaboration with Johns Hopkins School of Medicine in the USA.
24	Molecular Profiling of Temporal Lobe epilepsy Collaboration with: Dr. Akhilesh Pandey, Mr. Abhilash V, Institute of Bioinformatics, Bangalore Co-investigators: Dr.SK Shankar, Dr. Anita Mahadevan, Department of Neuropathology, NIMHANS, Prof P Satishchandra, Dept of Neurology, NIMHANS.(Published)
25	Effect of storage time, postmortem interval and gender difference on markers of antioxidant function and oxidative stress in postmortem human brains. Principal Investigator: Dr. MM Srinivas Bharath, Associate Professor, Mr. C Venkateshappa, Mr. G Harish Department of Neurochemistry, NIMHANS. Co-investigator: Dr.SK Shankar, Department of Neuropathology, Dr.Anita Mahadevan, Department of Neuropathology, NIMHANS. (Published)
26	Oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson’s disease brains Principal Investigator: Dr. MM Srinivas Bharath, Associate Professor, Rajeswara Babu Mythri, Mr. C Venkateshappa, Mr. G Harish Department of Neurochemistry, NIMHANS. Co-investigator: Dr.SK Shankar, Department of Neuropathology, Dr.Anita Mahadevan, Department of Neuropathology, NIMHANS. (Published)
27	Development of connectivity in the human auditory cortex Principal Investigator: Dr.Souwmya Iyengar, National Brain Research Centre, Manesar/HBTR, NIMHANS Co-investigator: Dr.SK Shankar, Department of Neuropathology, Dr.Anita Mahadevan, Department of Neuropathology, NIMHANS. (Published)
28	RO1 Project NIH, USA- Role of CNS opportunistic infections in subsequent development of HIV dementia” Principal Investigator: Dr.Carlos Pardo, Dept of Neurology, John Hopkins University, USA Co-PI: Dr.SK Shankar, Dr.Anita Mahadevan, Department of Neuropathology, NIMHANS Funded by: NIH, USA. (Published)
29	Subregional cytoarchitectural changes and cell cycle dysregulation in the hippocampus in patients with temporal lobe epilepsy Principal Investigator: Dr.Lily Pal, Addl.Prof. Dept of Pathology, SGPGI, Lucknow Co-PI: Dr.SK Shankar, Department of Neuropathology, Dr. P. Satishchandra, Dept. of Neurology, NIMHANS. Funded by: DST.(Completed)
30	ICMR Toxoplasma gondii genotypes in cerebral and extracerebral toxoplasmosis Principal Investigator: Dr.Jayashree, KMIO, Bangalore Co-investigator:Dr.S.K.Shankar, Dr.Anita Mahadevan, Dept of Neuropathology NIMHANS, Bangalore. Funded by: ICMR (Under review)
31	Biochemical and Histological Analysis of Traumatic Brain Injury in Neurotrauma Patients Principal Investigator: Dr. Srinivas Bharath, Assoc prof, Dept of neurochemistry, NIMHANS. Dr. Nupur Pruthi, Dept. of Neurosurgery, NIMHANS Co-investigator: Dr. S.K.Shankar & Dr. Anita Mahadevan, Dept. of Neuropathology, NIMHANS Funded by: ICMR (In-Progress)
32	Genomic, Proteomic and Transcriptomic Profiling of Tuberculous meningitis Principal Investigator: Dr.Akhilesh pandey, Dr.Raghothama Chaerkady, Institute of Bioinformatics, Bangalore Co-PI: Dr.SK Shankar, Dr Anita Mahadevan, Department of Neuropathology, NIMHANS Dr. P. Satishchandra, Dept. of Neurology, NIMHANS, Bangalore Funded by: DBT (Published)
33	Translational Research on the Neuroimmunopathology of Schizophrenia Principal Investigator: Dr.Venkatasubramanian, Associate Professor of Psychiatry, Dept of Psychiatry, NIMHANS. Co-PI: Dr. S.K.Shankar, Dr. Anita Mahadevan, Department of Neuropathology, NIMHANS. Supported by: DBT (In-Progress)
34	Establishment of skin biopsy for evaluation of peripheral neuropathies Principal Investigator: Dr.Anita Mahadevan, Addl Prof, Department of neuropathology Co-PI: Dr. P. Satishchandra & Dr.AB Taly, Dept. of Neurology, NIMHANS, Dr.SK Shankar, Emeritus Professor, Dept of neuropathology Funded by: DBT (In-Progress)
35	Characterization of host response to C. neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV infection. Principal Investigator: Dr. Keshav Prasad, Institute of Bioinformatics, Bangalore Co-PI: Dr.S.K.Shankar, Dr.Anita Mahadevan, Department of Neuropathology, NIMHANS. Funding Agency: DBT (Published)
36	Immunohistochemical studies of involvement of proinflammatory protein S100A9 intraumatic brain injury conditions. (In-Progress) Principal Investigator: Prof. Ludmilla A. Morozova-Roche , Professor in Medical biophysics
37	Diagnosis of Alzheimer’s disease using fluorescent probes Principal Investigator: Dr.T.Govindaraju, Assistant Professor, Bio-organic Chemistry Laboratory, JNCASR, Bangalore Co-PI: Dr.Anita Mahadevan, Dept of Neuropathology, NIMHANS, Bang alore. (In-Progress)
38	In vivo Protein Interaction Network of P.Falciparum from severe cerebral malaria patients. Principal Investigator: Namita Surolia, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur P.O. Bangalore. (In-Progress)
39	Identification of Cav 1.3 splice variants in SNpc in Parkinson’s disease. Principal Investigator: Prof. Vijayalakshmi Ravindranath, and Ms. Aditi Verma (PhD Scholar) Centre for Neuroscience, Indian Institute of Science,Bangalore. (In-Progress)
40	A retrospective study to evaluate genes expressed in Notch Pathway, prognosis and treatment response in gliomas (Provided Control brain tissues only) Principal Investigator: Dr. Rajeswari Narayanappa, Department of Biotechnology, DSCE, Bangalore
41	Development of Neuroscience Educational Material for popularizing Neuroscience under Human Brain Bank, NIMHANS Principal Investigator: Dr. S.K.Shankar, Emeritus Professor & Principal Co-ordinator, Human Brain Bank, Dept of Neuropathology, NIMHANS, Bangalore Co-PI: Dr. Anita Mahadevan, Addl. Professor, Dept. of Neuropathology, Associate Co- ordinator, Human Brain Bank, NIMHANS, Bangalore Funding Agency: ICMR (In-Progress)
42	Mapping the Protein Expression of Hippocampus, Amygdala and Temporal lobe in Adult Human Brain. Principal Investigator: Dr. Keshava Prasad, Institute of Bioinformatics, Bangalore Ph.D Scholar: Mrs. Praseeda Mol Co-PI:Dr.S.K.Shankar, Dr.Anita Mahadevan, Dept. of Neuropathology, NIMHANS (In-Progress)
43	A proteomic profile of human brain synaptosomes in Schizophrenia Principal Investigator: Dr. Keshava Prasad, Institute of Bioinformatics, Bangalore Ph.D Scholar: Lathika Gopalakrisha Co-PI: Dr.S.K.Shankar, Dr.Anita Mahadevan, Dept of Neuropathology, NIMHANS (In-Progress)
44	Host response profile of human brain proteome in toxoplasma encephalitis co-infected with HIV Principal Investigator: Dr. Keshava Prasad, Institute of Bioinformatics, Bangalore Ph.D Scholar: Apeksha Sahu Co-PI: Dr.S.K.Shankar, Dr.Anita Mahadevan, Dept of Neuropathology, NIMHANS (Published)
45	Proteome map of adult human pituitary glands Principal Investigator: Dr. Keshava Prasad, Institute of Bioinformatics, Bangalore Ph.D Scholar: Soujanya Co-PI:Dr.S.K.Shankar, DrAnita Mahadevan, Dept of Neuropathology,NIMHANS (Under review)
46	Characterization of human pineal gland proteome. (Accepted for publication) Principal Investigator: Dr. Keshava Prasad, Institute of Bioinformatics, Bangalore Ph.D Scholar: Soujanya Co-PI: Dr.S.K.Shankar, Dr.Anita Mahadevan, Dept of Neuropathology, NIMHANS.
47	Proteomic analysis for differential diagnosis of Guillain-Barré syndrome and paralytic rabies. (In-Progress) Principal Investigator: Dr. Keshava Prasad, Institute of Bioinformatics, Bangalore Ph.D Scholar: Peeyush Prasad Co-PI: Dr.Anita Mahadevan, Department of Neuropathology, NIMHANS
48	Human Brain Proteome: molecular insights into regional heterogeneity and neurological disorders. (In-Progress) Principal Investigator: Dr. Keshava Prasad, Institute of Bioinformatics, Bangalore Ph.D Scholar: Manjunath Co-PI: Dr.S.K.Shankar, Dr.Anita Mahadevan, Department of Neuropathology, NIMHANS
49	Proteomic profiling of olfactory Bulb/Tract. (In-Progress) Principal Investigator: Dr. Keshava Prasad, Institute of Bioinformatics,Bangalore Ph.D Scholar: Manjunath Co-PI: Dr.S.K.Shankar, Dr.Anita Mahadevan, Department of Neuropathology, NIMHANS
50	Pathomorphological changes in aging brain and comparison between Indian and Ceylon brains. (Published) Principal Investigator: Prof. Ranil K De Silva, Prinita Wijesinghe,. Genetic Diagnostic and Research Laboratory, Department of Anatomy, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka. Co-PI: Dr. Shankar SK, Dr.Chickabasaviah YT, NIMHANS.

Textbooks and Monographs

S.No	Name and Details
1	Creutzfeldt-Jakob disease: Indian perspective. Satishchandra P, Anita Mahadevan, SK Shankar. In: Progress in Clinical Neurosciences, VS Mehta, UK Mishra (eds). vol. XVI, 2001. Neurological Society of India, New Delhi.
2	Pathology of cerebral vasculature in Neurotuberculosis – some observations. SK Shankar, Vani Santosh, Anita Mahadevan, TC Yasha, P Satishchandra. In: Progress in Clinical Neurosciences, VS Mehta, UK Mishra (eds). vol. XVI, 2001. Neurological Society of India, New Delhi.
3	Molecular understanding of Aluminium Bio inorganic chemistry in relevance to the Pathology of Alzheimer’s Disease. S Anitha, P Shanmugavelu, Valeswara Rao, Gazula, SK Shankar, Ravi B Menon, RV Rao, Jagannatha KS Rao, Luigi Zecca : American Chemical Society Symposium series 822. Group 13 Chemistry. From Fundamentals to Applications. Edt.Shapiro PJ, Atwood DA. American Chemical Society, Washington. 2002. Chapter-16, p228-245
4	Shankar SK, Yasha TC. Neuropathology of Dementia. In: Handbook of Dementia, 2nd Edition. Kar N (eds). 2010.
5	Satishchandra P, Shankar SK, Anita Mahadevan. “Creutzfeldt – Jacob Disease”, Dementia Decoded Manjari Tripathi (Ed), Kontentwork 2014.
6	Anita Venketaramana, Nicoline Schiess, Anita Mahadevan, Shankar SK, Avindra Nath. Rabies. In: Clinical Infectious Diseases, Editor: David Schlossberg, Cambridge University Press, New York, NY (In Press)
7	Shankar S.K, Anita Mahadevan, Suresh Parmar. Histological Atlas of Common Infections of the Nervous System with Teaching Slides. Human Brain Tissue Repository, NIMHANS-ICMR, 2014.
8	Shankar S.K. in “ Slow Virus Infections and Prion Diseases” API Textbook of Medicine (2 vols) 10th Edition, Editor: Y.P.Munjal, 2015
9	Madakasira VP, Srivastava, Deepa Dash, Anita Mahadevan, Shankar SK. “Current concepts of Ischaemic Stroke”, Neurology in Tropics, 2nd Edition, Elsevier: 2015.
10	Anita Mahadevan, Satishchandra P, Shankar SK, “Measles Pathobiology and Central nervous system complications”,Neurology in Tropics, 2nd Edition, Elsevier: 2015